吴哲

邮箱:wuzhe@uestc.edu.cn

“千人计划”特聘教授、所长

电话:18080019322

教育背景:

1999-2005 美国罗切斯特大学 电子工程系 医学影像专业 博士

1995-1999 吉林大学 物理系 原子分子物理专业 学士

 

工作经历:

2017.5-至今 电子科技大学生命科学与技术学院 教授 ;电子科技大学医学装备研究所 所长

2013-至今 朗昇科技董事长;中科院声学所客座研究员; 中科院苏州医学工程研究所客座研究员

2010-2013 美国加州大学圣地亚哥分校医学院放射系助理教授;MOORES癌症研究中心研究员;超声分子影像学实验室主任

2005-2010 通用电气医疗北美总部 超声系统工程师

研究领域:

医疗超声影像


承担科研项目:

1.颈部超声自动扫描系统

2.超声人体运动意图精确识别技术、假肢康复、军用外骨骼系统

3.超高频超声换能器和成像系统及其在眼科的应用



代表性论文:

1. Hollow Iron-Silica Nanoshells for Enhanced High Intensity Focused Ultrasound, Alexander Liberman, Zhe Wu, Christopher V. Barback, Robert D. Viveros, James Wang, Lesley G. Ellies,  Robert F. Mattrey, William C. Trogler, Andrew C. Kummel, Sarah L. Blair, M Journal of Surgical Research May 2014

2. Applications of Perfluorocarbon Gas Loaded Iron-Silica Nanoshells in Ultrasound Guided Breast Cancer Surgery S.L. Blair, A. Lieberman, Z. Wu, D. Vera, R. Mattrey, W. Trogler, A. Kummel, A. Kummel Journal of Surgical Research Volume 186, Issue 2 , Page 503, February 2014

3. Emilia S Olson, Jahir Orozco,  Zhe Wu, Chris Malone,  Boemha Yi, Wei Gao, Mohammad Eghtedari, Joseph Wang, Robert Mattrey. 2013 Toward in vivo Detection of Hydrogen Peroxide with Ultrasound Molecular Imaging, Biomaterials Volume 34, Issue 35, November 2013, Pages 8918–8924

4. Liberman, Alexander, Zhe Wu, Christopher V. Barback, Robert Viveros, Sarah L. Blair, Lesley G. Ellies, David Vera, Robert Mattrey, Andrew C. Kummel, and William C. Trogler. "Color Doppler Ultrasound and Gamma Imaging of Intratumorally Injected 500 nm Iron-Silica Nanoshells." ACS Nano, 2013, 7 (7), pp 6367–6377

5. Alexander Liberman, H. Paul Martinez, Casey N. Ta, Christopher V. Barback, Robert F. Mattrey, Yuko Kono, Sarah L. Blair, William C. Trogler, Andrew C. Kummel, Zhe Wu* 2012 Hollow Silica and Silica-Boron Nano/Microparticles for Contrast-Enhanced Ultrasound to Detect Small Tumors, Biomaterials, 33 (2012), pp. 5124-5129

6. Casey N. Ta, Alexander Liberman, H. Paul Martinez, Christopher V. Barback, Robert F. Mattrey, Sarah L. Blair, William C. Trogler, Andrew C. Kummel, Zhe Wu* 2012  Integrated Processing of Contrast Pulse Sequencing Ultrasound Imaging for Enhanced Active Contrast of Hollow Gas Filled Silica Nano and Microshells, Journal of Vacuum Science and Technology B, 30(2), pp. 02C104-6 (2012). [This article was also selected by the Virtual Journal of Biological Physics Research -- April 1, 2012 Volume 23, Issue 7] 

7. Jun Zhang, Wen Hu and Zhe Wu 2009 Color Flow Image Segmentation SPIE 72650

8. Joyce McLaughlin, Daniel Renzi, Kevin Parker, and Zhe Wu 2007 Shear wave speed recovery using moving interference patterns obtained in sonoelastography experiments J. Acoust. Soc.Am 121 2438

9. M. Zhang, B. Castaneda, Z. Wu , P. Nigwekar, J. Joseph, D. Rubens, K. Parker 2007 Congruence of imaging estimators and mechanical measurements of viscoelastic properties of soft tissues Ultrasound In Medicine and Biology 33 1617-1631

10. Zhe Wu, Kenneth Hoyt, Deborah J. Rubens, and Kevin J. Parker 2006 Sonoelastographic imaging of interference patterns for estimation of shear velocity distribution in biomaterials J. Acoust. Soc. Am. 120 535

11. L. Taylor, D. Rubens, B. Porter, Z. Wu, R. Baggs, P. di Sant'Agnese, G. Nadasdy, D. Pasternack and K. Parker 2005 Prostate cancer: three-dimensional sonoelastography for in vitro detection Radiology 237 981-985

12. Wu Z, Taylor LS, Rubens DJ, Parker KJ 2004 Sonoelastographic imaging of interference patterns for estimation of the shear velocity of homogeneous biomaterials Physics In Medicine and Biology 49 911-922

13. L. Taylor, B. Porter, G. Nadasdy, P. DiSant'Agnese, D. Pasternack, Z. Wu, R. Baggs, D.Rubens and K. Parker 2004 Three-dimensional registration of prostate images from histology and ultrasound Ultrasound in Medicine and Biology 30 161-168

14. Wu Z, Taylor LS, Rubens DJ, Parker KJ 2002 shear wave focusing for three-dimensional sonoelastography J. Acoust. Soc. Am 111 439-446

 

专利:

1.Degradable Silica Nanoshells for Ultrasonic Imaging/Therapy WO2014052911A1

2.Method and System for in vivo Hydrogen Peroxide (H2O2) detection with ultrasound, 61/658,325

3.Real time visualization of shear wave propagation in soft materials with sonoelastography, 7,444,875

4.Apparatus, system, and method for adaptively controlling a frame interval between ultrasound scanning frames for an ultrasound elasticity imaging scan,8123692B2

 






研究成果转化情况介绍:

独立开发世界上最小的超声成像模块并将之集成成为国内首款取得药监局注册的掌上彩超设备